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Grants to USA, Canada, and International Nonprofits,
Agencies, and IHEs for Research Related to Blood Cancers

Drug Repurposing Clinical Trials to Impact Blood Cancers

Agency Type:

Foundation / Corporation

Funding Source:

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Cures Within Reach (CWR) - CureAccelerator

Deadline Date:

05/20/22

Description:

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Grants of up to $75,000 to USA, Canada, and International nonprofit, government research, and academic institutions for research related to blood cancers. Funding is intended for proof of concept clinical trials related to repurposed treatments for unsolved blood cancers.

This Request for Proposals (RFP) from Cures Within Reach (CWR) is seeking repurposed treatments to address unsolved blood cancers. We are interested in generic or proprietary drugs that could be repurposed to create "new" treatments to 1) reduce the symptoms, progression or incidence of; 2) restore function lost to; or 3) reduce or eliminate severe side effects of currently used therapies for any blood cancer, thereby improving patient outcomes and quality of life.

Repurposed therapies must be approved and/or generally recognized as safe for human use by some regulatory agency, such as the US Food and Drug Administration, European Medicines Agency, Health Canada or Japan’s Pharmaceuticals and Medical Devices Agency.

Eligible clinical repurposing trials may also:

  • Test combination therapies to increase their efficacy, including combining the current disease treatment with a repurposed treatment or combining multiple repurposed therapies
  • Repurpose therapies approved for use in adults into pediatric indications, or vice versa

An unsolved blood cancer is one in which one or more of the following are true:

  • There is currently no effective treatment
  • The current treatment is only effective for a portion of the patient population
  • There is a treatment that is effective, but many patients develop resistance to the therapy
  • There is a treatment that is effective for the entire patient population, but the treatment is very expensive, and therefore some patients cannot get access to the treatment
  • There is a treatment that is effective for the entire patient population with significant side effects, and for some patients the negative side effects outweigh the benefits of the treatment

GrantWatch ID#:

GrantWatch ID#: 202017

Estimated Size of Grant:

Minimum: $50,000
Maximum: $75,000.

Term of Contract:

Only interventional clinical trials lasting no more than 36 months are eligible for this funding.

Additional Eligibility Criteria:

This RFP is open to accredited academic, nonprofit and governmental research institutions and/or health systems significantly involved with medical research located anywhere in the world, where good scientific research and clinical practices can be assured. Although start-ups, biotechs, pharmaceutical companies and medical device companies are not eligible for this RFP, their collaborators at eligible institutions can apply. Contact Clare Thibodeaux, PhD to learn more.

CWR is interested in supporting both previously funded investigators and early-stage investigators and who have received little or no extramural research funding to date. PIs who have not received extramural funding previously and/or who do not currently have their own lab should include a Letter of Support from a funded, senior researcher who will act as a mentor for the proposed clinical trial and the investigator.

Pre-Application Information:

Proposal Submissions Due: May 20, 2022

Principal Investigators (PIs) will be contacted approximately 6-8 weeks following the proposal submission deadline with a decision.

Cures Within Reach will provide no more than 80% of the requested project funding, and the institution or organization proposing the research will match at least 20% of the requested project funding.

FAQs: https://cureaccelerator.org/faq/

Contact Information:

Before starting your grant application, please review the funding source's website listed below for updates/changes/addendums/conferences/LOIs.

Application: https://app.cureaccelerator.org/registration

If you have a repurposing idea in any unsolved blood cancer that isn't an exact fit for this RFP, or if you have eligibility questions due to budget or other aspects, please contact Clare Thibodeaux, PhD at clare@cureswithinreach.org to discuss fit and/or submission options.

Cures Within Reach
134 N. LaSalle, #1130
Chicago, IL 60602
info@cureswithinreach.org

URL for Full Text (RFP):

Geographic Focus:

USA: Alabama;   Alaska;   Arizona;   Arkansas;   California;   Colorado;   Connecticut;   Delaware;   Florida;   Georgia;   Hawaii;   Idaho;   Illinois;   Indiana;   Iowa;   Kansas;   Kentucky;   Louisiana;   Maine;   Maryland;   Massachusetts;   Michigan;   Minnesota;   Mississippi;   Missouri;   Montana;   Nebraska;   Nevada;   New Hampshire;   New Jersey;   New Mexico;   New York City;   New York;   North Carolina;   North Dakota;   Ohio;   Oklahoma;   Oregon;   Pennsylvania;   Rhode Island;   South Carolina;   South Dakota;   Tennessee;   Texas;   Utah;   Vermont;   Virginia;   Washington, DC;   Washington;   West Virginia;   Wisconsin;   Wyoming

Array ( [0] => American Samoa (USA); [1] => Guam (USA); [2] => Puerto Rico (USA); [3] => Virgin Islands (USA); [4] => Northern Mariana Islands (USA); )

USA Territories: American Samoa (USA);   Guam (USA);   Puerto Rico (USA);   Virgin Islands (USA);   Northern Mariana Islands (USA);

USA Compact Free Associations: The Federated States of Micronesia (USA)   Marshall Islands (USA)   Republic of Palau (USA)

Canada: Alberta;   British Columbia;   Manitoba;   New Brunswick;   Newfoundland and Labrador;   Northwest Territories;   Nova Scotia;   Nunavut;   Ontario;   Prince Edward Island;   Quebec;   Saskatchewan;   Yukon;

Israel

International country outside of the USA, Israel and Canada.

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